article proves the existence of a hyper-precise global numerical
meta-architecture unifying, structuring, binding and controlling the billion
triplet codons constituting the sequence of
single-stranded DNA of the entire human genome. Beyond the evolution and
erratic mutations like transposons within the genome, it’s as if the memory of
a fossil genome with multiple symmetries persists. This recalls the “intermingling” of information characterizing the
fractal universe of chaos theory. The result leads to a balanced and perfect
tuning between the masses of the two strands of the huge DNA molecule that
constitute our genome. We show here how codon populations forming the
single-stranded DNA sequences can constitute a critical approach to the
understanding of junk DNA function. Then, we suggest revisiting certain methods
published in our 2009 book “Codex Biogenesis”. In fact, we demonstrate here how
the universal genetic code table is a powerful analytical filter to
characterize single-stranded DNA sequences constituting chromosomes and
genomes. We can then show that any genomic DNA sequence is featured by three numbers,
which characterize it and its 64 codon populations with correlations greater
than 99%. The number “1” is
common to all sequences, expressing the second law of Chargaff. The other 2
numbers are related to each specific DNA sequence case characterizing life
species. For example, the entire human genome is characterized by three remarkable
numbers 1, 2, and Phi = 1.618 the golden ratio. Associated with each of these
three numbers, we can match three axes of symmetry, then “imagine” a kind of
hyperspace formed by these codon populations. Then we revisit the value (3-Phi)/2
which is probably universal and common to both the scale of quarks and atomic
levels, balancing and tuning the whole human genome codon population. Finally,
we demonstrate a new kind of duality between “form and substance” overlapping
the whole human genome: we will show that—simultaneously with the duality
between genes and junk DNA—there is a second layer of embedded hidden structure
overlapping all the DNA of the whole human genome, dividing it into a second
type of duality information/redundancy involving golden ratio proportions.
Cite this paper
J. Perez, "The “3 Genomic Numbers” Discovery: How Our Genome Single-Stranded DNA Sequence Is “Self-Designed” as a Numerical Whole," Applied Mathematics
, Vol. 4 No. 10, 2013, pp. 37-53. doi: 10.4236/am.2013.410A2004
 S. V. Petoukhov and V. I. Svirin, “Fractal Genetic Nets and Symmetry Principles in Long Nucleotide Sequences,” Symmetrion, Vol. 23, No. 3 4, 2013, pp. 303 322
 J. C. Perez, “Codex Biogenesis,” 2009.
 International Human Genome Project Sequencing Centers and Verified by NCBI and UCSC, “Human Genome Fi nalized BUILD34. Build 34 Finished Human Genome Assembly,” 2003.
 A. J. Pellionisz, R. Graham, P. A. Pellionisz and J. C. Perez, “Recursive Genome Function of the Cerebellum: Geometric Unification of Neuroscience and Genomics,” In: M. Manto, D. L. Gruol, J. D. Schmahmann, N. Koibu chi and F. Rossi, Eds., Handbook of the Cerebellum and Cerebellar Disorders, 2012, pp. 1381 1423.
http://fr.scribd.com/doc/111439455/BOOK Unification of Neuroscience and Genomics Pellionisz Et Al in Section 4
 J. C. Perez, “Decoding Non Coding DNA Codes: Human Genome Meta Chromosomes Architecture,” BIT Life Sci ences’ 3rd Annual World Vaccine Congress, Beijing, 23 25 March 2011.
 Website Dedicated to DNA Pioneers, “Chargaff in Linus Pauling and the Race of DNA”.
 G. Bernardi, Website Dedicated to Pr Bernardi Research. http://www.giorgiobernardi.it
 G. Bernardi, “Isochores,” In: Encyclopedia of Life Sci ences, John Wiley and Sons, Ltd., Chichester, 2012.
 R. Durbin, “The 1000 Genomes Project,” Wellcome Trust Sanger Institute, 2012.
 Morrisson Institute for Population and Resources Studies (Stanford University), “Stanford Human Genome Diver sity Project,” 2011.
http://hsblogs.stanford.edu/morrison/human genome diversity project
 L. Luca Cavalli Sforza, “Opinion: The Human Genome Diversity Project: Past, Present and Future,” Nature Re views Genetics, Vol. 6, No. 4, 2005, pp. 333 340.
 C. T. Zhang, R. Zhang and H. Y. Ou, “The Z Curve Data Base: A Graphic Representation of Genome Sequences,” Bioinformatics, Vol. 19, No. 5, 2002, pp. 593 599.
 J. C. Perez, “Codon Populations in Single Stranded Whole Human Genome DNA Are Fractal and Fine Tuned by the Golden Ratio 1.618,” Interdisciplinary Sciences: Compu tational Life Sciences, Vol. 2, No. 3, 2010, pp. 1 13.
http://fr.scribd.com/doc/95641538/Codon Populations in Single stranded Whole Human Genome DNA Are Frac tal and Fine tuned by the Golden Ratio 1 618
 J. Sola Soler, “Phi and Music in DNA,” 2012.
http://www.sacred geometry.es/en/content/and much more?q=en/content/phi and music dna
 J. Gielen, “The Story of Just Not PI, Archimedes Was Too Fast,” 2013. http://quarks divided.over blog.fr
 P. Marshall, “Checksum Discovered in DNA (The Ma thematics of DNA),” 2012.
perry marshall checksum discovered in dna the mathematics of dna thankstobin
 N. Tidjani, “A Quantum Like Approach to the Genetic Code,” Neuroquantology, Vol. 9, No. 4, 2011, pp. 785 798.
 J. C. Perez, “Chromosome 4: Breakthoughs in Evolution, Longevity and Cancers,” Unpublished, 2013.
 T. Bardini, “JUNKware,” University of Minesota Press, Minneapolis, 2011.
 L Montagnier, et al., “DNA Waves and Water,” Journal of Physics: Conference Series, Vol. 306, 2011, Article ID: 012007.
 D. Hofstadter, “Godel Escher Bach,” 1979.
 M. C. Escher, “Bond of Union 1956 Lithograph”.
 P. Marcer, “Communications: Order and Chaos in DNA —The Denis Guichard Prizewinner: Jean Claude Perez,” Kybernetes, Vol. 21, No. 2, 1992, pp. 60 61.
 J. C. Perez, “Chaos, DNA and Neuro Computers: A Gol den Link,” Speculations in Science and Technology, Vol. 14, No. 4, 1991, pp. 336 346.
http://golden ratio in dna.blogspot.fr/2008/01/1991 first publication related to.html
 J. C. Perez, “L’ADN Décrypté,” 1997.
http://www.resurgence.be/91 adn decrypte97828.72110179.html
 J. C. Perez, “Scale Invariance Embedded Votes and Self Emerging Binary Logics in the Whole Human Genome,” 2008, Relating the Paper: What Is Complexity? By P. M. Gell Mann, Complexity, Vol. 1, No. 1, 1995, pp. 16 19.
http://www.scribd.com/doc/68476137/JcperezLiveBitsFromDNA from John NASH Logics to J C PEREZ Fractals Biomathematics
 J. C. Perez, “Golden Ratio and Numbers in DNA,” 2008.
http://golden ratio in dna.blogspot.fr
 J. C. Perez, “Various Other Publications,” 2013.
 J. C. Perez, “Caminos Interdisciplinarios,” Espacio Inter disciplinario, Seminario en_clave Inter, Universitad de la Republica, Montevideo, Uruguay, 26 28 Octubre 2011.
 R. Friedman and M. Cross, “The Golden Ratio § Fibo nacci Sequence: Golden Keys to Your Genius, Health, Wealth § Excellence,” Hoslin Media Company Stanford US, 2013, pp. 579 598.
http://www.amazon.com/The Golden Ratio Fibonacci Sequence/dp/1939623006
 Claudio Martinez Debat, “ADN y Arte Transgenico,” 2013.
 Aya, “School of Sacred Geometry,” 2012.